Practical Textbook of Experimental Pharmacology

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Publisher: Prime Publishing House
ISBN: 9789395596299
Year: 2023
Pages: 88

Practical Textbook of Experimental Pharmacology is a comprehensive and student-friendly laboratory manual designed to develop essential practical skills in pharmacology. Written in simple and clear language, the book provides a systematic approach to understanding experimental techniques and procedures used in pharmacological studies.

The book covers fundamental aspects such as an introduction to experimental pharmacology, study of commonly used laboratory animals, and detailed descriptions of instruments and techniques. It also explains various routes of drug administration, types of pre-clinical experiments, and methods of blood collection, helping students gain a strong practical foundation.

Special emphasis is given to hands-on experiments including the study of drug effects such as local anaesthetics, mydriatic and miotic responses, analgesic activity, and screening of anti-convulsants, muscle relaxants, and central nervous system agents. It further includes important experiments on isolated organs, ciliary motility, and pyrogen testing.

Designed to bridge the gap between theory and practice, this book serves as a valuable resource for students and educators, enabling them to understand experimental procedures, interpret results, and develop proficiency in pharmacological research techniques.

1. Introduction to experimental pharmacology.
2. Study of laboratory animals (a) Mice, (b) Rat, (c) Guinea pigs, (d) Rabbit
3. Commonly used instruments in experimental pharmacology
4. Different routes of administration of drugs in animals
5. Types of pre-clinical experiments : In-Vivo, In-Vitro, Ex-Vivo, etc.
6. Techniques of blood collection from animals
7. Study of local anaesthetics on rabbit eye
8. Study of Mydriatic effect on rabbit eye.
9. Study of Miotic effect on rabbit eye.
10. Effect of analgesics using Analgesiometer
11. Study of analgesic activity by writhing test
12. Screening of anti-convulsant using Electro Convulsiometer
13. Screening of Muscle relaxants using Rota-Rod apparatus.
14. Screening of CNS stimulants and depressants using Actophotometer.
15. Study of anxiolytic activity using elevated plus maze method.
16. Study of effect of Acetylcholine on isolated heart.
17. Study of effect of Adrenaline on isolated heart
18. Effect of drugs on ciliary motility on frog’s buccal cavity
19. Pyrogen testing by rabbit method.

A book as per the latest syllabus frame under Education Regulation 2020 Prescribe for D.Pharmacy, Second Year by Pharmacy Council of India (PCI)

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