This book on Novel Drug Delivery Systems presents a clear, concise, and student-friendly approach to understanding advanced drug delivery techniques used in modern pharmaceutical sciences. The content is carefully organized and simplified with the help of illustrations, flow charts, and examples, enabling learners to grasp complex concepts with ease and interest.
The book comprehensively covers various innovative delivery systems including controlled drug delivery, polymer-based systems, microencapsulation, mucosal and transdermal delivery, implantable systems, gastroretentive systems, nasopulmonary delivery, and targeted drug delivery approaches. It also includes specialized topics such as ocular and intrauterine drug delivery systems, providing a broad and in-depth understanding of emerging technologies in this field.
Each section is designed to strengthen conceptual clarity and is supported with question banks comprising long and short answer questions to aid in effective preparation. With its lucid language and structured presentation, this book serves as a valuable resource for students and teachers, helping to build a strong foundation and enhance knowledge in novel drug delivery systems.
1. Controlled Drug Delivery System
1.1 Introduction
1.2 Terminology/definitions and rationale
1.3 Advantages and disadvantages
1.4 Selection of drug candidates
1.5 Approaches to design controlled release formulations
1.6 Physicochemical and biological properties of drugs
2. Polymers
2.1 Introduction
2.2 Classification
2.3 Properties
2.4 Advantages and Application of Polymers
3. Microencapsulation
3.1 Definition
3.2 Advantages and Disadvantages
3.3 Microspheres/microcapsules
3.4 Microparticles
3.5 Methods of microencapsulation
3.6 Applications
4. Mucosal Drug Delivery
4.1 Introduction
4.2 Principles of bioadhesion / mucoadhesion
4.3 Concepts
4.4 Advantages and Disadvantages
4.5 Transmucosal permeability and formulation considerations of buccal delivery systems
5. Implantable Drug Delivery Systems
5.1 Introduction
5.2 Advantages and Disadvantages
5.3 Concept of implants and osmotic pump
6. Transdermal Drug Delivery Systems
6.1 Introduction
6.2 Permeation through skin
6.3 Factors affecting permeation
6.4 Permeation enhancers
6.5 Basic components of TDDS
6.6 Formulation Approaches
7. Gastroretentive Drug Delivery Systems
7.1 Introduction
7.2 Advantages and Disadvantages
7.3 Approaches for GRDDS
7.4 Applications
8. Nasopulmonary Drug Delivery System
8.1 Introduction
8.2 Formulation of Inhalers (dry powder and metered dose)
8.3 Nasal sprays
8.4 Nebulizers
9. Targeted Drug Delivery System
9.1 Concepts and Approaches
9.2 Advantages and Disadvantages
9.3 Liposomes
9.4 Niosomes
9.5 Nanoparticles
9.6 Monoclonal Antibodies
9.7 Applications of TDDS
10. Ocular Drug Delivery Systems
10.1 Introduction
10.2 Intraocular Barriers Methods to Overcome
10.3 Preliminary Study, Ocular Formulations and Ocuserts
11. Intrauterine Drug Delivery Systems
11.1 Introduction
11.2 Advantages and disadvantages
11.3 Development of intra uterine devices
11.4 Application
A book as per the latest syllabus given by Pharmacy Council of India (PCI) New Delhi
for B.Pharm students of all Indian Universities