Author:
Dr Sushil D Patil
Publisher:
Prime Publishing House
ISBN:
9789395596091
Year:
2022
Pages:
268
“Medicinal Chemistry–I” is a comprehensive and student-friendly book that provides a clear understanding of the fundamental concepts of medicinal chemistry in a simple and systematic manner. The book is designed to help readers grasp the essential principles of drug design, classification, mechanism of action, and therapeutic applications with clarity and ease.
The text begins with an introduction to medicinal chemistry, covering its history, development, and the significance of physicochemical properties such as solubility, ionization, and protein binding in relation to biological activity. It also explains the principles of drug metabolism, including Phase I and Phase II reactions and factors influencing metabolic processes.
The book further explores drugs acting on the autonomic nervous system, detailing adrenergic and cholinergic neurotransmitters, their receptors, and structure–activity relationships of important drug classes. It provides a systematic study of sympathomimetic and parasympathomimetic agents, along with cholinergic blocking agents and their pharmacological significance.
In addition, the content covers drugs acting on the central nervous system, including sedatives, hypnotics, antipsychotics, anticonvulsants, and anesthetics. Key drug categories are discussed with emphasis on their chemical structures, mechanisms, and therapeutic uses, enabling a strong conceptual understanding.
With its structured presentation and focus on both theoretical and practical aspects, this book serves as a valuable resource for building a solid foundation in medicinal chemistry and supports learners in understanding the relationship between chemical structure and biological activity.
A book as per the latest syllabus given by Pharmacy Council of India (PCI) New Delhi
for B.Pharm students of all Indian Universities
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